Sequence 2 from Patent US 20030077289

General Information


DRACP ID  DRACP01238

Peptide Name   Sequence 2 from Patent US 20030077289

Sequence  SVYDFFVWL

Sequence Length  9

UniProt ID  P40126  P29812  Q70LM6 

PubChem CID  Not available

Origin  Human

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Antitumor



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01238

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C61H78N10O14

Absent amino acids  ACEGHIKMNPQRT

Common amino acids  FV

Mass  131822

Pl  3.75

Basic residues  0

Acidic residues  1

Hydrophobic residues  6

Net charge  -1

Boman Index  903

Hydrophobicity  125.56

Aliphatic Index  107.78

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  6990

Absorbance 280nm  873.75

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2003/0077289 A1

Patent Title  Use of cell-penetrating peptides to generate antitumor immunity.

Other Iinformation  Granted Patent Family: 6s / 6ex; Family Jurisdictions: CN, WO, AU, US; Legal Status: Discontinued; Application No: 7755502; Filed:Feb 15, 2002; Published: Apr 24, 2003; Earliest Priority: Feb 15, 2001

Other Published ID  CN1309417C  CN1503628A  WO2002064057A2  WO2002064057A3 




DRACP is developed by Dr.Zheng's team.