Sequence 2 from Patent US 20030077289
General Information
DRACP ID DRACP01238
Peptide Name Sequence 2 from Patent US 20030077289
Sequence SVYDFFVWL
Sequence Length 9
UniProt ID P40126 P29812 Q70LM6
PubChem CID Not available
Origin Human
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C61H78N10O14
Absent amino acids ACEGHIKMNPQRT
Common amino acids FV
Mass 131822
Pl 3.75
Basic residues 0
Acidic residues 1
Hydrophobic residues 6
Net charge -1
Boman Index 903
Hydrophobicity 125.56
Aliphatic Index 107.78
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 6990
Absorbance 280nm 873.75
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2003/0077289 A1
Patent Title Use of cell-penetrating peptides to generate antitumor immunity.
Other Iinformation Granted Patent Family: 6s / 6ex; Family Jurisdictions: CN, WO, AU, US; Legal Status: Discontinued; Application No: 7755502; Filed:Feb 15, 2002; Published: Apr 24, 2003; Earliest Priority: Feb 15, 2001
Other Published ID CN1309417C CN1503628A WO2002064057A2 WO2002064057A3