Sequence 10 from Patent US 20040043936
General Information
DRACP ID DRACP01251
Peptide Name Sequence 10 from Patent US 20040043936
Sequence CVHTYRA
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Sos scrofus (Pig)
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C36H56N12O10S
Absent amino acids DEFGIKLMNPQSW
Common amino acids ACHRTVY
Mass 95618
Pl 8.53
Basic residues 2
Acidic residues 0
Hydrophobic residues 2
Net charge 2
Boman Index -1516
Hydrophobicity -17.14
Aliphatic Index 55.71
Half Life
Mammalian: 1.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 248.33
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2004/0043936 A1
Patent Title Antiproliferative and antiviral proteins and peptides.
Other Iinformation Granted Patent Family: 11s / 14ex; Family Jurisdictions: EP, IL, AU, US, AT, DE; Legal Status: Expired; Application No: 67049003; Filed:Sep 25, 2003; Published: Mar 4, 2004; Earliest Priority: Jul 2, 1998; Granted: Jan 13, 2009
Other Published ID DE69937998D1 DE69937998T2 EP1091753A1 EP1091753A4 EP1091753B1 US7476649