Sequence 3 from Patent US 20050239703

General Information


DRACP ID  DRACP01253

Peptide Name   Sequence 3 from Patent US 20050239703

Sequence  ELKCYTCKEPMTSAACRTIT

Sequence Length  20

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01253

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C93H157N25O31S4

Absent amino acids  DFGHNQVW

Common amino acids  T

Mass  258874

Pl  8.04

Basic residues  3

Acidic residues  2

Hydrophobic residues  4

Net charge  1

Boman Index  -3381

Hydrophobicity  -22.5

Aliphatic Index  49

Half Life 
  Mammalian: 1.2 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1615

Absorbance 280nm  85

Polar residues  9

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2005/0239703 A1

Patent Title  Anticancer peptide compositions.

Other Iinformation  Granted Patent Family: 3s / 3ex; Family Jurisdictions: US, WO; Legal Status: Inactive; Application No: 97762904; Filed:Oct 29, 2004; Published: Oct 27, 2005; Earliest Priority: Oct 29, 2003; Granted: Feb 5, 2008

Other Published ID  US7326679  WO2005042001A1 




DRACP is developed by Dr.Zheng's team.