Sequence 3 from Patent US 20070293424
General Information
DRACP ID DRACP01296
Peptide Name Sequence 3 from Patent US 20070293424
Sequence GGGGWGQGGTHG
Sequence Length 12
UniProt ID B5SY89 P40242 Q6EH52 Q5UJG7 Q5UJG3 P40243
PubChem CID Not available
Origin Tragelaphus strepsiceros
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antimicrobial, Antitumor, Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C42H58N16O15
Absent amino acids ACDEFIKLMNPRSVY
Common amino acids G
Mass 122342
Pl 7.55
Basic residues 1
Acidic residues 0
Hydrophobic residues 1
Net charge 1
Boman Index -292
Hydrophobicity -95.83
Aliphatic Index 0
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 500
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2007/0293424 A1
Patent Title Antitumoral and Antiviral Peptides.
Other Iinformation Granted Patent Family: 10s / 10ex; Family Jurisdictions: EP, RU, AU, ZA, US, WO; Legal Status: Active; Application No: 58571504 ; Filed:Dec 30, 2004; Published: Dec 20, 2007; Earliest Priority: Jan 15, 2004; Granted: Feb 12, 2013
Other Published ID EP1705182A1 EP1705182A4 EP1705182B1 US8372406 WO2005068491A1