Sequence 4 from Patent US 20070293424
General Information
DRACP ID DRACP01298
Peptide Name Sequence 4 from Patent US 20070293424
Sequence GGGWGQPHVGG
Sequence Length 11
PubChem CID Not available
Origin Tragelaphus strepsiceros
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antimicrobial, Antitumor, Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C44H61N15O13
Absent amino acids ACDEFIKLMNRSTY
Common amino acids G
Mass 118662
Pl 7.55
Basic residues 1
Acidic residues 0
Hydrophobic residues 2
Net charge 1
Boman Index 181
Hydrophobicity -67.27
Aliphatic Index 26.36
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 550
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2007/0293424 A1
Patent Title Antitumoral and Antiviral Peptides.
Other Iinformation Granted Patent Family: 10s / 10ex; Family Jurisdictions: EP, RU, AU, ZA, US, WO; Legal Status: Active; Application No: 58571504 ; Filed:Dec 30, 2004; Published: Dec 20, 2007; Earliest Priority: Jan 15, 2004; Granted: Feb 12, 2013
Other Published ID EP1705182A1 EP1705182A4 EP1705182B1 US8372406 WO2005068491A1