This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 11 from Patent US 20070293424
General Information
DRACP ID DRACP01299
Peptide Name Sequence 11 from Patent US 20070293424
Sequence HGGGWGQGGGTHS
Sequence Length 13
UniProt ID Q9Z0T3 P40256 P61766 P40257 P04156 P40251 P40252 P40247
PubChem CID Not available
Origin Homo sapiens
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antimicrobial, Antitumor, Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C49H67N19O17
Absent amino acids ACDEFIKLMNPRVY
Common amino acids G
Mass 140842
Pl 7.72
Basic residues 2
Acidic residues 0
Hydrophobic residues 1
Net charge 2
Boman Index -1192
Hydrophobicity -116.15
Aliphatic Index 0
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 458.33
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2007/0293424 A1
Patent Title Antitumoral and Antiviral Peptides.
Other Iinformation Granted Patent Family: 10s / 10ex; Family Jurisdictions: EP, RU, AU, ZA, US, WO; Legal Status: Active; Application No: 58571504 ; Filed:Dec 30, 2004; Published: Dec 20, 2007; Earliest Priority: Jan 15, 2004; Granted: Feb 12, 2013
Other Published ID EP1705182A1 EP1705182A4 EP1705182B1 US8372406 WO2005068491A1
This work is licensed under a Creative Commons Attribution 4.0 International License.