This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 10 from Patent US 20070293424
General Information
DRACP ID DRACP01301
Peptide Name Sequence 10 from Patent US 20070293424
Sequence HGGGWGQPHGGGWG
Sequence Length 14
UniProt ID B5SY89 Q5UJG1 Q5UJH8 P40242 Q6EH52 Q5UJG7 Q5UJG3 P40258 P49927 B0FYL5 P52114 P40244 P52113 P23907 Q95M08 P67986 Q5XVM4 O18754 Q68G95 P47852 P79141 O46501 Q9Z0T3 Q60506 Q60468
PubChem CID Not available
Origin Homo sapiens
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antimicrobial, Antitumor, Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C60H75N21O16
Absent amino acids ACDEFIKLMNRSTVY
Common amino acids G
Mass 157846
Pl 7.72
Basic residues 2
Acidic residues 0
Hydrophobic residues 2
Net charge 2
Boman Index -268
Hydrophobicity -117.86
Aliphatic Index 0
Half Life
Mammalian: 3.5 hour
Yeast: 10 min
E.coli: >10 hour
Extinction Coefficient cystines 11000
Absorbance 280nm 846.15
Polar residues 8
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2007/0293424 A1
Patent Title Antitumoral and Antiviral Peptides.
Other Iinformation Granted Patent Family: 10s / 10ex; Family Jurisdictions: EP, RU, AU, ZA, US, WO; Legal Status: Active; Application No: 58571504 ; Filed:Dec 30, 2004; Published: Dec 20, 2007; Earliest Priority: Jan 15, 2004; Granted: Feb 12, 2013
Other Published ID EP1705182A1 EP1705182A4 EP1705182B1 US8372406 WO2005068491A1
This work is licensed under a Creative Commons Attribution 4.0 International License.