This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 2 from Patent US 20100279918
General Information
DRACP ID DRACP01306
Peptide Name Sequence 2 from Patent US 20100279918
Sequence CPGPEGAGC
Sequence Length 9
UniProt ID Q9JJG0 A2VEC9 P98167 Q700K0 Q8CG65
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys1<--->Cys13
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C30H47N9O12S2
Absent amino acids DFHIKLMNQRSTVWY
Common amino acids G
Mass 93276
Pl 3.85
Basic residues 0
Acidic residues 1
Hydrophobic residues 1
Net charge -1
Boman Index 38
Hydrophobicity -12.22
Aliphatic Index 11.11
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 125
Absorbance 280nm 15.63
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2010/0279918 A1
Patent Title Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents.
Other Iinformation Granted Patent Family: 7s / 7ex; Family Jurisdictions: DE, EP, WO, AT, US; Legal Status: Discontinued; Application No: 22536707; Filed:Mar 20, 2007; Published: Nov 4, 2010; Earliest Priority: Mar 20, 2006;
Other Published ID DE602007011901D1 EP1991586A1 EP1991586B1 WO2007108749A1 WO2007108749A8
This work is licensed under a Creative Commons Attribution 4.0 International License.