This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 17 from Patent US 20100279918
General Information
DRACP ID DRACP01309
Peptide Name Sequence 17 from Patent US 20100279918
Sequence GALFLGWLGAAGSTMGAPKKKRKV
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C112H186N32O27S
Absent amino acids CDEHINQY
Common amino acids G
Mass 285541
Pl 12
Basic residues 5
Acidic residues 0
Hydrophobic residues 10
Net charge 5
Boman Index -469
Hydrophobicity 5.83
Aliphatic Index 77.5
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 239.13
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2010/0279918 A1
Patent Title Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents.
Other Iinformation Granted Patent Family: 7s / 7ex; Family Jurisdictions: DE, EP, WO, AT, US; Legal Status: Discontinued; Application No: 22536707; Filed:Mar 20, 2007; Published: Nov 4, 2010; Earliest Priority: Mar 20, 2006;
Other Published ID DE602007011901D1 EP1991586A1 EP1991586B1 WO2007108749A1 WO2007108749A8
This work is licensed under a Creative Commons Attribution 4.0 International License.