Sequence 4 from Patent US 20100279918

General Information


DRACP ID  DRACP01311

Peptide Name   Sequence 4 from Patent US 20100279918

Sequence  GRKKRRQRRRPPQ

Sequence Length  13

UniProt ID  P35965  P20879  Q73370  P04613  P04610  P69697 

PubChem CID  Not available

Origin  Human immunodeficiency vi

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01311

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C70H131N35O16

Absent amino acids  ACDEFHILMNSTVWY

Common amino acids  R

Mass  193323

Pl  13.2

Basic residues  8

Acidic residues  0

Hydrophobic residues  0

Net charge  8

Boman Index  -11076

Hydrophobicity  -349.23

Aliphatic Index  0

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2010/0279918 A1

Patent Title  Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents.

Other Iinformation  Granted Patent Family: 7s / 7ex; Family Jurisdictions: DE, EP, WO, AT, US; Legal Status: Discontinued; Application No: 22536707; Filed:Mar 20, 2007; Published: Nov 4, 2010; Earliest Priority: Mar 20, 2006;

Other Published ID  DE602007011901D1  EP1991586A1  EP1991586B1  WO2007108749A1  WO2007108749A8 




DRACP is developed by Dr.Zheng's team.