This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 4 from Patent US 20100279918
General Information
DRACP ID DRACP01311
Peptide Name Sequence 4 from Patent US 20100279918
Sequence GRKKRRQRRRPPQ
Sequence Length 13
UniProt ID P35965 P20879 Q73370 P04613 P04610 P69697
PubChem CID Not available
Origin Human immunodeficiency vi
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C70H131N35O16
Absent amino acids ACDEFHILMNSTVWY
Common amino acids R
Mass 193323
Pl 13.2
Basic residues 8
Acidic residues 0
Hydrophobic residues 0
Net charge 8
Boman Index -11076
Hydrophobicity -349.23
Aliphatic Index 0
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2010/0279918 A1
Patent Title Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents.
Other Iinformation Granted Patent Family: 7s / 7ex; Family Jurisdictions: DE, EP, WO, AT, US; Legal Status: Discontinued; Application No: 22536707; Filed:Mar 20, 2007; Published: Nov 4, 2010; Earliest Priority: Mar 20, 2006;
Other Published ID DE602007011901D1 EP1991586A1 EP1991586B1 WO2007108749A1 WO2007108749A8
This work is licensed under a Creative Commons Attribution 4.0 International License.