This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 7 from Patent US 20100279918
General Information
DRACP ID DRACP01316
Peptide Name Sequence 7 from Patent US 20100279918
Sequence RVIRVWFQNKRCKDKK
Sequence Length 16
UniProt ID G5EC36 P53409 P50480 P53406 Q96A47 Q9CXV0 P53408 P53407 P61371 P53405 P50211 P50212 P53410
PubChem CID Not available
Origin Rattus sp.
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C94H158N32O21S
Absent amino acids AEGHLMPSTY
Common amino acids K
Mass 237228
Pl 11.72
Basic residues 7
Acidic residues 1
Hydrophobic residues 5
Net charge 6
Boman Index -6827
Hydrophobicity -139.38
Aliphatic Index 60.63
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 366.67
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2010/0279918 A1
Patent Title Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents.
Other Iinformation Granted Patent Family: 7s / 7ex; Family Jurisdictions: DE, EP, WO, AT, US; Legal Status: Discontinued; Application No: 22536707; Filed:Mar 20, 2007; Published: Nov 4, 2010; Earliest Priority: Mar 20, 2006;
Other Published ID DE602007011901D1 EP1991586A1 EP1991586B1 WO2007108749A1 WO2007108749A8
This work is licensed under a Creative Commons Attribution 4.0 International License.