This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 18 from Patent US 20100279918
General Information
DRACP ID DRACP01317
Peptide Name Sequence 18 from Patent US 20100279918
Sequence WEAKLAKALAKALAKHLAKALAKALKACEA
Sequence Length 30
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C144H248N40O35S
Absent amino acids DFGIMNPQRSTVY
Common amino acids A
Mass 364938
Pl 10.68
Basic residues 8
Acidic residues 2
Hydrophobic residues 19
Net charge 6
Boman Index -228
Hydrophobicity 28.33
Aliphatic Index 118
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 189.66
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2010/0279918 A1
Patent Title Chimeric Constructs Between Cancer-Homing Peptides and Cell-Penetrating Peptides Coupled to Anticancer Drugs and/or Diagnostic Agent/Agents.
Other Iinformation Granted Patent Family: 7s / 7ex; Family Jurisdictions: DE, EP, WO, AT, US; Legal Status: Discontinued; Application No: 22536707; Filed:Mar 20, 2007; Published: Nov 4, 2010; Earliest Priority: Mar 20, 2006;
Other Published ID DE602007011901D1 EP1991586A1 EP1991586B1 WO2007108749A1 WO2007108749A8
This work is licensed under a Creative Commons Attribution 4.0 International License.