Sequence 17 from Patent US 20110159022
General Information
DRACP ID DRACP01325
Peptide Name Sequence 17 from Patent US 20110159022
Sequence AQTQRIRCRV
Sequence Length 10
UniProt ID P21741 A5DCV3 B5Z8L0 Q1CS51 O25812 Q9ZK11 Q17VM4
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C49H91N21O14S
Absent amino acids DEFGHKLMNPSWY
Common amino acids R
Mass 139117
Pl 12.2
Basic residues 3
Acidic residues 0
Hydrophobic residues 3
Net charge 3
Boman Index -4636
Hydrophobicity -82
Aliphatic Index 78
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0159022 A1
Patent Title Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.
Other Iinformation Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;
Other Published ID CA2728459A1 CN102123731A EP2296697A1 WO2009153463A1