This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 28 from Patent US 20110159022
General Information
DRACP ID DRACP01338
Peptide Name Sequence 28 from Patent US 20110159022
Sequence GTKVRQGTLKKARYN
Sequence Length 15
UniProt ID P21741
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C74H130N26O21
Absent amino acids CDEFHIMPSW
Common amino acids K
Mass 196990
Pl 11.77
Basic residues 5
Acidic residues 0
Hydrophobic residues 3
Net charge 5
Boman Index -5130
Hydrophobicity -142.67
Aliphatic Index 52
Half Life
Mammalian: 1 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 106.43
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0159022 A1
Patent Title Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.
Other Iinformation Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;
Other Published ID CA2728459A1 CN102123731A EP2296697A1 WO2009153463A1
This work is licensed under a Creative Commons Attribution 4.0 International License.