This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 25 from Patent US 20110159022
General Information
DRACP ID DRACP01341
Peptide Name Sequence 25 from Patent US 20110159022
Sequence KEFGADCKYKFENWG
Sequence Length 15
UniProt ID P21741
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C84H116N20O24S
Absent amino acids HILMPQRSTV
Common amino acids K
Mass 207192
Pl 6.4
Basic residues 3
Acidic residues 3
Hydrophobic residues 4
Net charge 0
Boman Index -3251
Hydrophobicity -125.33
Aliphatic Index 6.67
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 6990
Absorbance 280nm 499.29
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0159022 A1
Patent Title Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.
Other Iinformation Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;
Other Published ID CA2728459A1 CN102123731A EP2296697A1 WO2009153463A1
This work is licensed under a Creative Commons Attribution 4.0 International License.