This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 31 from Patent US 20110159022
General Information
DRACP ID DRACP01352
Peptide Name Sequence 31 from Patent US 20110159022
Sequence PKYVKQNTLKLAT
Sequence Length 13
UniProt ID Q03909 P03435 P03449 P03438 P03439 P03442 P03437 Q2RFA5 Q91MA7 Q1PUD9 P26139 Q2RCH5 P03436 P03440 P19106 P26141 Q2VNF2 Q2VND2 P12583 Q30NQ1 P12584 P03441 P12588 P12585 P12582
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C69H118N18O19
Absent amino acids CDEFGHIMRSW
Common amino acids K
Mass 171803
Pl 10.64
Basic residues 3
Acidic residues 0
Hydrophobic residues 4
Net charge 3
Boman Index -1842
Hydrophobicity -72.31
Aliphatic Index 90
Half Life
Mammalian: 1.4 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 124.17
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0159022 A1
Patent Title Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.
Other Iinformation Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;
Other Published ID CA2728459A1 CN102123731A EP2296697A1 WO2009153463A1
This work is licensed under a Creative Commons Attribution 4.0 International License.