Sequence 10 from Patent US 20110159022

General Information


DRACP ID  DRACP01354

Peptide Name   Sequence 10 from Patent US 20110159022

Sequence  RGFLLLTLLALLALT

Sequence Length  15

UniProt ID  P21741 

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01354

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C79H138N18O18

Absent amino acids  CDEHIKMNPQSVWY

Common amino acids  L

Mass  187800

Pl  10.55

Basic residues  1

Acidic residues  0

Hydrophobic residues  11

Net charge  1

Boman Index  2684

Hydrophobicity  203.33

Aliphatic Index  221.33

Half Life 
  Mammalian: 0.8 hour
  Yeast: 10 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2011/0159022 A1

Patent Title  Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.

Other Iinformation  Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;

Other Published ID  CA2728459A1  CN102123731A  EP2296697A1  WO2009153463A1 




DRACP is developed by Dr.Zheng's team.