This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 37 from Patent US 20110319336
General Information
DRACP ID DRACP01364
Peptide Name Sequence 37 from Patent US 20110319336
Sequence EWLS
Sequence Length 4
UniProt ID M9MRD1 O01761 Q9UPN3 Q9QXZ0 Q54QG5 D3ZHV2 Q63HN8 D4AU56 Q70LM4 S0DLP2 Q14204 Q9JHU4 P38650 P37276 Q19020 Q9MBF8 Q8BW94 Q63170 Q8WXX0 A0A482N9V7 Q9YN02 Q8B912 Q9WJB2 Q06502 Q830
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C25H35N5O8
Absent amino acids ACDFGHIKMNPQRTVY
Common amino acids ELSW
Mass 58727
Pl 3.85
Basic residues 0
Acidic residues 1
Hydrophobic residues 2
Net charge -1
Boman Index -296
Hydrophobicity -35
Aliphatic Index 97.5
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 1833.33
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0319336 A1
Patent Title Selective anticancer chimeric peptide.
Other Iinformation Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013
Other Published ID CN102238965A EP2370107A2 WO2010064207A2 WO2010064207A3
This work is licensed under a Creative Commons Attribution 4.0 International License.