This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 54 from Patent US 20110319336
General Information
DRACP ID DRACP01368
Peptide Name Sequence 54 from Patent US 20110319336
Sequence KCCYSL
Sequence Length 6
UniProt ID P25648
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C30H49N7O9S2
Absent amino acids ADEFGHIMNPQRTVW
Common amino acids C
Mass 80525
Pl 8.22
Basic residues 1
Acidic residues 0
Hydrophobic residues 1
Net charge 1
Boman Index -161
Hydrophobicity 46.67
Aliphatic Index 65
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1615
Absorbance 280nm 323
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0319336 A1
Patent Title Selective anticancer chimeric peptide.
Other Iinformation Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013
Other Published ID CN102238965A EP2370107A2 WO2010064207A2 WO2010064207A3
This work is licensed under a Creative Commons Attribution 4.0 International License.