This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 26 from Patent US 20110319336
General Information
DRACP ID DRACP01375
Peptide Name Sequence 26 from Patent US 20110319336
Sequence KQLIRFLKRLDRN
Sequence Length 13
UniProt ID P51492 P46652 Q865Y0 P79339 P05112
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C76H134N26O18
Absent amino acids ACEGHMPSTVWY
Common amino acids LR
Mass 191429
Pl 12.24
Basic residues 5
Acidic residues 1
Hydrophobic residues 5
Net charge 4
Boman Index -5410
Hydrophobicity -100.77
Aliphatic Index 120
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0319336 A1
Patent Title Selective anticancer chimeric peptide.
Other Iinformation Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013
Other Published ID CN102238965A EP2370107A2 WO2010064207A2 WO2010064207A3
This work is licensed under a Creative Commons Attribution 4.0 International License.