This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 12 from Patent US 20110319336
General Information
DRACP ID DRACP01388
Peptide Name Sequence 12 from Patent US 20110319336
Sequence RLLRRLLRRLLRRLLRRLLR
Sequence Length 20
UniProt ID P9WPT9 P59947 A6NCM1
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C120H232N50O21
Absent amino acids ACDEFGHIKMNPQSTVWY
Common amino acids LR
Mass 305056
Pl 13.45
Basic residues 10
Acidic residues 0
Hydrophobic residues 10
Net charge 10
Boman Index -10000
Hydrophobicity -35
Aliphatic Index 195
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0319336 A1
Patent Title Selective anticancer chimeric peptide.
Other Iinformation Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013
Other Published ID CN102238965A EP2370107A2 WO2010064207A2 WO2010064207A3
This work is licensed under a Creative Commons Attribution 4.0 International License.