This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 38 from Patent US 20110319336
General Information
DRACP ID DRACP01391
Peptide Name Sequence 38 from Patent US 20110319336
Sequence SNEW
Sequence Length 4
UniProt ID C6KTB7 P0C6X1 P98158 P98164 P0C6U2 Q86UP3 Q9JJN2 Q9VB11 Q558W4 Q54TW0 Q558Y6 Q86AE3 B0G0Z9 A0A0B4K7J2 Q6ZS30 Q21920 B0G101 Q86JI5 B0G103 Q6EWG9 Q6EVZ2 Q54YH4 Q9VXE6 A1XG13 A1DF
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C23H30N6O9
Absent amino acids ACDFGHIKLMPQRTVY
Common amino acids ENSW
Mass 58821
Pl 3.85
Basic residues 0
Acidic residues 1
Hydrophobic residues 1
Net charge -1
Boman Index -1452
Hydrophobicity -217.5
Aliphatic Index 0
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 1833.33
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0319336 A1
Patent Title Selective anticancer chimeric peptide.
Other Iinformation Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013
Other Published ID CN102238965A EP2370107A2 WO2010064207A2 WO2010064207A3
This work is licensed under a Creative Commons Attribution 4.0 International License.