Sequence 15 from Patent US 20110319336

General Information


DRACP ID  DRACP01400

Peptide Name   Sequence 15 from Patent US 20110319336

Sequence  YCDGFYACYMDVGGGKLlLKlLkkLLKlLKKK

Sequence Length  32

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  l=D-Leucine; k=D-Lysine

Chiral  Mix



Physicochemical Information


Formula  C143H221N33O30S3

Absent amino acids  EHINPQRSTW

Common amino acids  KL

Mass  353186

Pl  9.66

Basic residues  6

Acidic residues  2

Hydrophobic residues  9

Net charge  4

Boman Index  -414

Hydrophobicity  8.13

Aliphatic Index  85.31

Half Life 
  /

Extinction Coefficient cystines  4595

Absorbance 280nm  148.23

Polar residues  9

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2011/0319336 A1

Patent Title  Selective anticancer chimeric peptide.

Other Iinformation  Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013

Other Published ID  CN102238965A  EP2370107A2  WO2010064207A2  WO2010064207A3 




DRACP is developed by Dr.Zheng's team.