Sequence 21 from Patent US 20110319336

General Information


DRACP ID  DRACP01402

Peptide Name   Sequence 21 from Patent US 20110319336

Sequence  YHWYGYTPQNVIGGGGGRLLRRLLRRLLRK

Sequence Length  30

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01402

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C163H262N54O37

Absent amino acids  ACDEFMS

Common amino acids  GLR

Mass  408766

Pl  12.22

Basic residues  8

Acidic residues  0

Hydrophobic residues  9

Net charge  8

Boman Index  -6845

Hydrophobicity  -63.67

Aliphatic Index  100.67

Half Life 
  Mammalian: 2.8 hour
  Yeast: 10 min
  E.coli: 2 min

Extinction Coefficient cystines  9970

Absorbance 280nm  343.79

Polar residues  11

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2011/0319336 A1

Patent Title  Selective anticancer chimeric peptide.

Other Iinformation  Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013

Other Published ID  CN102238965A  EP2370107A2  WO2010064207A2  WO2010064207A3 




DRACP is developed by Dr.Zheng's team.