DRACP ID  DRACP01486

Peptide Name   Sequence 62 from Patent US 20120328692

Sequence  XPLAXEALXR

Sequence Length  10

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer

PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  X(1) = Trp with F, Cl, Br, I, CH3, CF3, CN, OH, or NO2 at position 6 or position 7, or both positions 6 and 7 where the side group is the same or different; X(5) = Phe with F, Cl, Br, I, CH3, CF3, CN, OH, or NO2 at position 4; X(9) = Leu with F, Cl, Br, I, CH3, CF3, CN, OH, or NO2 at positions gamma, delta1 or delta2

Chiral  L

Amino acid distribution

Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2012/0328692 A1

Patent Title  Potent D-peptide antagonists of mdm2 and mdmx for anticancer therapy.

Other Iinformation  Granted Patent Family: 8s / 8ex; Family Jurisdictions: CN, DK, US, EP, ES; Legal Status: Active; Application No: 16168397; Filed:May 4, 2016; Published: Jul 17, 2019; Earliest Priority: May 7, 2015; Granted: Jul 17, 2019

Other Published ID  Not available