This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 8 from Patent US 20200079827
General Information
DRACP ID DRACP01499
Peptide Name Sequence 8 from Patent US 20200079827
Sequence ILKKWWKTSKGLLGGLLGGVTSVIKKLKKI
Sequence Length 30
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C158H274N40O35
Absent amino acids ACDEFHMNPQRY
Common amino acids K
Mass 381163
Pl 11.65
Basic residues 8
Acidic residues 0
Hydrophobic residues 13
Net charge 8
Boman Index 538
Hydrophobicity 22.33
Aliphatic Index 136.33
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 11000
Absorbance 280nm 379.31
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2020/0079827 A1
Patent Title Novel Antimicrobial And Anti-cancer Therapy
Other Iinformation Granted Patent Family: 6s / 6ex; Family Jurisdictions: EP, IL, AU, US, AT, DEUS, EP, CN, WO; Legal Status: Active; Application No: 201716462586; Filed:Nov 21, 2017; Published: Mar 12, 2020; Earliest Priority: Nov 21, 2016; Granted: Mar 29, 2022
Other Published ID WO2018094403A1 CN109996554A EP3541405A1 EP3541405A4
This work is licensed under a Creative Commons Attribution 4.0 International License.