Sequence 1 from Patent US 4529594
General Information
DRACP ID DRACP01539
Peptide Name Sequence 1 from Patent US 4529594
Sequence SASRALSDKPLAHVVANPQVEGQLQWL
Sequence Length 27
UniProt ID P04924
PubChem CID Not available
Origin Synthetic construct
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C129H208N38O39
Absent amino acids CFIMTY
Common amino acids AL
Mass 337926
Pl 7.55
Basic residues 3
Acidic residues 2
Hydrophobic residues 12
Net charge 1
Boman Index -3181
Hydrophobicity -16.67
Aliphatic Index 104.81
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 211.54
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 4529594 A
Patent Title Protein having antitumor activity.
Other Iinformation Granted Patent Family: 8s / 8ex; Family Jurisdictions: EP, JP, US, DE; Legal Status: Expired; Application No: 62985384; Filed: Jul 11, 1984; Published: Jul 16, 1985; Earliest Priority: Jul 15, 1983; Granted: Jul 16, 1985
Other Published ID DE3462506D1 EP0132125A2 EP0132125A3 EP0132125B1 EP0132125B2