FLAK94

General Information


DRACP ID  DRACP01680

Peptide Name   FLAK94

Sequence  FALALKA

Sequence Length  7

UniProt ID  Not available

PubChem CID  Not available

Origin  FLAK peptides

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
MCF-7 Invasive breast carcinoma of no special type Carcinoma LD50=430 µg/ml MTT assay 24 h Patent
SW480 Colon adenocarcinoma Carcinoma LD50=560 µg/ml MTT assay 24 h Patent
BMKC Skin carcinoma Carcinoma LD50=465 µg/ml MTT assay 24 h Patent
BMKC Skin carcinoma Carcinoma LD50=465 µg/ml MTT assay 24 h Patent
NCI-H1299 Lung large cell carcinoma Carcinoma LD50=1000 µg/ml MTT assay 24 h Patent
PC-3 Prostate carcinoma Carcinoma Not available MTT assay 24 h Patent
HeLa Human papillomavirus-related endocervical adenocarcinoma Carcinoma LD50>1000 µg/ml MTT assay 24 h Patent

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01680

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C36H60N8O8

Absent amino acids  CDEGHIMNPQRSTVWY

Common amino acids  A

Mass  84014

Pl  9.7

Basic residues  1

Acidic residues  0

Hydrophobic residues  6

Net charge  1

Boman Index  1270

Hydrophobicity  170

Aliphatic Index  154.29

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US2005/0209157A1

Patent Title  Short bioactive peptides and methods for their use

Other Iinformation  Patent Application; Family: 1s / 24ex; Family Jurisdictions: US; Legal Status: Discontinued; Application No: 13618605; Filed: May 24, 2005; Published: Sep 22, 2005; Earliest Priority: Mar 28, 2001

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.