FLAK50 Q1V
General Information
DRACP ID DRACP01737
Peptide Name FLAK50 Q1V
Sequence VAKFLAKFLKKAL
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin FLAK peptides
Type Synthetic peptide
Classification
Active ACP
Activity Information
Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
---|---|---|---|---|---|---|
MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | LD50=92 µg/ml | MTT assay | 24 h | Patent |
SW480 | Colon adenocarcinoma | Carcinoma | Not available | MTT assay | 24 h | Patent |
BMKC | Skin carcinoma | Carcinoma | Not available | MTT assay | 24 h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C74H125N17O14
Absent amino acids CDEGHIMNPQRSTWY
Common amino acids K
Mass 169115
Pl 11.28
Basic residues 4
Acidic residues 0
Hydrophobic residues 9
Net charge 4
Boman Index 799
Hydrophobicity 84.62
Aliphatic Index 135.38
Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US2005/0209157A1
Patent Title Short bioactive peptides and methods for their use
Other Iinformation Patent Application; Family: 1s / 24ex; Family Jurisdictions: US; Legal Status: Discontinued; Application No: 13618605; Filed: May 24, 2005; Published: Sep 22, 2005; Earliest Priority: Mar 28, 2001
Other Published ID Not available