Peptide Libraray

D2A21V

General Information

DRACP ID DRACP01738

Peptide Name D2A21V

Sequence VAKKFAKKFKKFAKKFAKFAFAF

Sequence Length 23

UniProt ID Not available

PubChem CID Not available

Origin FLAK peptides

Type Synthetic peptide

Classification

Active ACP

Activity Information

Cell Line	Disease	Cancer Classified	Activity	Assay	Testing Time	Literature
MCF-7	Invasive breast carcinoma of no special type	Carcinoma	LD50=210 µg/ml	MTT assay	24 h	Patent
SW480	Colon adenocarcinoma	Carcinoma	Not available	MTT assay	24 h	Patent
BMKC	Skin carcinoma	Carcinoma	Not available	MTT assay	24 h	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Nature Anticancer; Antibacterial; Antifungal

Structure Information

PDB ID Not available

Predicted Structure DRACP01738

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Amidation

Other Modification None

Chiral L

Physicochemical Information

Formula C140H212N32O24

Absent amino acids CDEGHILMNPQRSTWY

Common amino acids K

Mass 312001

Pl 11.7

Basic residues 9

Acidic residues 0

Hydrophobic residues 14

Net charge 9

Boman Index -1419

Hydrophobicity -2.17

Aliphatic Index 38.7

Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour

Extinction Coefficient cystines 0

Absorbance 280nm 0

Polar residues 0

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US2005/0209157A1

Patent Title Short bioactive peptides and methods for their use

Other Iinformation Patent Application; Family: 1s / 24ex; Family Jurisdictions: US; Legal Status: Discontinued; Application No: 13618605; Filed: May 24, 2005; Published: Sep 22, 2005; Earliest Priority: Mar 28, 2001

Other Published ID Not available