This work is licensed under a Creative Commons Attribution 4.0 International License.
SEQ ID NO: 4
General Information
DRACP ID DRACP01758
Peptide Name SEQ ID NO: 4
Sequence WRYMVm
Sequence Length 6
UniProt ID Not available
PubChem CID Not available
Origin Not available
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| CT26 | Mouse colon adenocarcinoma | Carcinoma | 2 μg/mouse of WRYMVm successfully inhibited tumor mass growth (50% against PBS control) on day 22. | Tumor growth assay | Not available | Patent |
| EL4 | Mouse precursor T cell lymphoblastic lymphoma/leukemia | Lymphoma | As shown in FIGS. 10A and 10B, WRYMVm was able to suppress tumor mass of EL4 | Tumor growth assay | Not available | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification m=D-Methionine
Chiral Mix
Physicochemical Information
Formula C36H49N9O6S
Absent amino acids ACDEFGHIKLNPQST
Common amino acids MRVWY
Mass 82526
Pl 9.35
Basic residues 1
Acidic residues 0
Hydrophobic residues 2
Net charge 1
Boman Index -634
Hydrophobicity -10
Aliphatic Index 48.33
Half Life
/
Extinction Coefficient cystines 6990
Absorbance 280nm 1398
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US2009/0118197A1
Patent Title Immune-Modulating Peptide
Other Iinformation Patent Application; Family: 15s / 15ex; Family Jurisdictions: KR, US, EP, CA, CN, JP, WO; Legal Status: Active; Application No: 24622908; Filed: Oct 6, 2008; Published: May 7, 2009; Earliest Priority: Jan 29, 2002; Granted: Sep 13, 2011
Other Published ID CA2634902A1 CA2634902C CN101370510A CN101370510B EP1976545A1 EP1976545B1 JP2009520812A JP4880700B2 KR101040299B1 KR20080071194A US2007219139A1 US7517857B2 US8017572B2 WO2007073127A1
This work is licensed under a Creative Commons Attribution 4.0 International License.