Sequence 1 from Patent US 20060100147
General Information
DRACP ID DRACP01759
Peptide Name Sequence 1 from Patent US 20060100147
Sequence YLCAGRNDCIIAIKFEEKTAQHAAIENVFRLE
Sequence Length 32
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C162H257N45O48S2
Absent amino acids MPSW
Common amino acids A
Mass 422037
Pl 5.66
Basic residues 5
Acidic residues 5
Hydrophobic residues 14
Net charge 0
Boman Index -5102
Hydrophobicity -3.13
Aliphatic Index 97.81
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1615
Absorbance 280nm 52.1
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US20090203594
Patent Title Anticancer peptide.
Other Iinformation Patent Application Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Discontinued; Application No: 286507; Filed: Dec 19, 2007; Published: Aug 13, 2009; Earliest Priority: Sep 20, 2004
Other Published ID US20090203594