AQTGTGKT

General Information


DRACP ID  DRACP01761

Peptide Name   AQTGTGKT

Sequence  AQTGTGKT

Sequence Length  8

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetics

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
SNU-387 Adult hepatocellular carcinoma; Adult hepatocellular carcinoma Carcinoma As shown in FIG. 1B, both two types of peptides inhibited the resistance to anticancer drugs in all the cancer cell lines MTT assay 1 h Patent
Malme-3M Melanoma Carcinoma As shown in FIG. 1B, both two types of peptides inhibited the resistance to anticancer drugs in all the cancer cell lines MTT assay 1 h Patent

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  CAGE protein

Nature  Anticancer; Antitumor



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01761

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C30H54N10O13

Absent amino acids  CDEFHILMNPRSVWY

Common amino acids  T

Mass  88786

Pl  9.7

Basic residues  1

Acidic residues  0

Hydrophobic residues  1

Net charge  1

Boman Index  -1511

Hydrophobicity  -106.25

Aliphatic Index  12.5

Half Life 
  Mammalian: 1 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US2018/0057532A1

Patent Title  Peptide Having Eight Amino Acid Sequences Derived From Cage and Retaining Anticancer Activity and Activity to Promote Anticancer Drug Sensitivity of Anticancer Drug-Resistant Cancer Cells

Other Iinformation  Patent Application; Family: 5s / 5ex; Family Jurisdictions: US, WO; Legal Status: Active; Application No: 201715624906; Filed: Jun 16, 2017; Published: Mar 1, 2018; Earliest Priority: Dec 18, 2014; Granted: Mar 26, 2019

Other Published ID  US10233221B2  US10239924B2  US2018079792A1  WO2016099188A1 




DRACP is developed by Dr.Zheng's team.