This work is licensed under a Creative Commons Attribution 4.0 International License.
D-AQTGTGKT
General Information
DRACP ID DRACP01762
Peptide Name D-AQTGTGKT
Sequence D-AQTGTGKT
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Synthetics
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| SNU-387 | Adult hepatocellular carcinoma; Adult hepatocellular carcinoma | Carcinoma | As shown in FIG. 1B, both two types of peptides inhibited the resistance to anticancer drugs in all the cancer cell lines | MTT assay | 1 h | Patent |
| Malme-3M | Melanoma | Carcinoma | As shown in FIG. 1B, both two types of peptides inhibited the resistance to anticancer drugs in all the cancer cell lines | MTT assay | 1 h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism CAGE protein
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C34H57N11O15
Absent amino acids CEFHILMNPRSVWY
Common amino acids T
Mass 102061
Pl 6.34
Basic residues 1
Acidic residues 1
Hydrophobic residues 1
Net charge 0
Boman Index -2383
Hydrophobicity -120
Aliphatic Index 10
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US2018/0057532A1
Patent Title Peptide Having Eight Amino Acid Sequences Derived From Cage and Retaining Anticancer Activity and Activity to Promote Anticancer Drug Sensitivity of Anticancer Drug-Resistant Cancer Cells
Other Iinformation Patent Application; Family: 5s / 5ex; Family Jurisdictions: US, WO; Legal Status: Active; Application No: 201715624906; Filed: Jun 16, 2017; Published: Mar 1, 2018; Earliest Priority: Dec 18, 2014; Granted: Mar 26, 2019
Other Published ID US10233221B2 US10239924B2 US2018079792A1 WO2016099188A1
This work is licensed under a Creative Commons Attribution 4.0 International License.