Not available

General Information


DRACP ID  DRACP01819

Peptide Name   Not available

Sequence  KAMKSIAKFIAK

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetics

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HeLa Human papillomavirus-related endocervical adenocarcinoma Carcinoma At the concentration of 40umol/L, 20umol/L and 5umol/L, the peptide can inhibit more than 80% of HeLa cells MTT assay Not available Patent

Hemolytic Activity  37% of red blood cells lysed at 200umol

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01819

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C62H110N16O14S

Absent amino acids  CDEGHLNPQRTVWY

Common amino acids  K

Mass  153211

Pl  11.28

Basic residues  4

Acidic residues  0

Hydrophobic residues  6

Net charge  4

Boman Index  -500

Hydrophobicity  22.5

Aliphatic Index  90

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID WO2009/015602A1

Patent Title  Polypeptides Having Anticancer Activity

Other Iinformation  Patent Application; Family: 10s / 10ex; Family Jurisdictions: WO, CN, EP, JP, US; Legal Status: Pending; Application No: 2008071804; Filed: Jul 30, 2008; Published: Feb 5, 2009; Earliest Priority: Jul 31, 2007

Other Published ID  CN100590130C  CN101168563A  EP2184295A1  EP2184295A4  EP2184295B1  JP2010534689A  JP5707594B2  US2010145012A1  US8207122B2 




DRACP is developed by Dr.Zheng's team.