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Not available
General Information
DRACP ID DRACP01821
Peptide Name Not available
Sequence KGWFKAMKSIAKFIAKEKMKEHL
Sequence Length 23
UniProt ID Not available
PubChem CID Not available
Origin Synthetics
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | When the peptide concentration is 40μmol/L, the cell growth inhibition rate is about 0.97. | MTT assay | Not available | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C129H209N33O29S2
Absent amino acids CDNPQRTVY
Common amino acids K
Mass 314300
Pl 10.93
Basic residues 8
Acidic residues 2
Hydrophobic residues 9
Net charge 6
Boman Index -2641
Hydrophobicity -52.17
Aliphatic Index 63.91
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 250
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID WO2009/015602A1
Patent Title Polypeptides Having Anticancer Activity
Other Iinformation Patent Application; Family: 10s / 10ex; Family Jurisdictions: WO, CN, EP, JP, US; Legal Status: Pending; Application No: 2008071804; Filed: Jul 30, 2008; Published: Feb 5, 2009; Earliest Priority: Jul 31, 2007
Other Published ID CN100590130C CN101168563A EP2184295A1 EP2184295A4 EP2184295B1 JP2010534689A JP5707594B2 US2010145012A1 US8207122B2
This work is licensed under a Creative Commons Attribution 4.0 International License.