This work is licensed under a Creative Commons Attribution 4.0 International License.
FGF2 derived peptides
General Information
DRACP ID DRACP01836
Peptide Name FGF2 derived peptides
Sequence KRTGQYKLGSKT
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin API13 derived peptides
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| Ca Ski | Human papillomavirus-related cervical squamous cell carcinoma; Squamous cell carcinoma of the cervix uteri | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| Hep 3B2.1-7 | Childhood hepatocellular carcinoma; Pediatric hepatocellular carcinoma | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| PLC/PRF/5 | Adult hepatocellular carcinoma; | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| ACHN | Papillary renal cell carcinoma | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| Caki-2 | Papillary renal cell carcinoma | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| Mia PaCa-2 | Pancreatic ductal adenocarcinoma | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
| AsPC-1 | Pancreatic ductal adenocarcinoma | Carcinoma | As shown in Figure 26, anticancer effects of API5-derived peptides (API5) or FGF2-derived peptides (FGF2) on cervical cancer, liver cancer, kidney cancer, or pancreatic cancer cell lines were confirme | MTT assay | 48 h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C59H103N19O18
Absent amino acids ACDEFHIMNPVW
Common amino acids K
Mass 156296
Pl 11.13
Basic residues 4
Acidic residues 0
Hydrophobic residues 1
Net charge 4
Boman Index -3899
Hydrophobicity -168.33
Aliphatic Index 32.5
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 135.45
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID WO2021/025352A1
Patent Title Anticancer Virus Expressing Fgf2- or Api5-Derived Peptide, and Use Thereof
Other Iinformation Patent Application; Family: 3s / 3ex; Family Jurisdictions: WO, KR; Legal Status: Pending; Application No: 2020009856; Filed: Jul 27, 2020; Published: Feb 11, 2021; Earliest Priority: Aug 8, 2019
Other Published ID KR102241134B1 KR20210017560A
This work is licensed under a Creative Commons Attribution 4.0 International License.