Desotamide C

General Information


DRACP ID  DRACP01858

Peptide Name   Desotamide C

Sequence  XGNIlL

Sequence Length  6

UniProt ID  Not available

PubChem CID  118712037  

Origin  Streptomyces scopuliridis SCSIO ZJ47

Type  Native peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
Hep-G2 Hepatoblastoma Blastoma IC50>100 µM SRB assay Not available 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  NCB: X1<--->Leu6

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  X=N-formyl-kynurenine; l=D-Leu

Chiral  Mix



Physicochemical Information


Formula  C18H29N5O4

Absent amino acids  ACDEFHKMPQRSTVWY

Common amino acids  GILNX

Mass  57883

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  2

Net charge  0

Boman Index  414

Hydrophobicity  73.33

Aliphatic Index  130

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25072108

Title  Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria

Doi 10.1021/np500399v

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPN_11148

DRACP is developed by Dr.Zheng's team.