This work is licensed under a Creative Commons Attribution 4.0 International License.
Desotamide D
General Information
DRACP ID DRACP01859
Peptide Name Desotamide D
Sequence XGNIlL
Sequence Length 6
UniProt ID Not available
PubChem CID 118712038
Origin Streptomyces scopuliridis SCSIO ZJ48
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Hep-G2 | Hepatoblastoma | Blastoma | IC50>100 µM | SRB assay | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: X1<--->Leu6
N-terminal Modification Free
C-terminal Modification Free
Other Modification X=kynurenine; l=D-Leu
Chiral Mix
Physicochemical Information
Formula C18H29N5O4
Absent amino acids ACDEFHKMPQRSTVWY
Common amino acids GILNX
Mass 57883
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index 414
Hydrophobicity 73.33
Aliphatic Index 130
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25072108
Title Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPN_11149
This work is licensed under a Creative Commons Attribution 4.0 International License.