This work is licensed under a Creative Commons Attribution 4.0 International License.
KFAK(1)
General Information
DRACP ID DRACP01860
Peptide Name KFAK(1)
Sequence KFAK
Sequence Length 4
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 112% Killing=500µg/ml | MTS assay | 24 h | Patent |
Hemolytic Activity RBCs: 2.8%Hemolysis=250 µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C24H40N6O5
Absent amino acids CDEGHILMNPQRSTVWY
Common amino acids K
Mass 54631
Pl 10.81
Basic residues 2
Acidic residues 0
Hydrophobic residues 2
Net charge 2
Boman Index -631
Hydrophobicity -80
Aliphatic Index 25
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7091185B2
Patent Title Periodic antimicrobial peptides
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006
Other Published ID US2005187151A1
External Code
DBAASP ID DBAASPS_13351
This work is licensed under a Creative Commons Attribution 4.0 International License.