This work is licensed under a Creative Commons Attribution 4.0 International License.
KFAK(2)
General Information
DRACP ID DRACP01861
Peptide Name KFAK(2)
Sequence KFAKKFAK
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 83% Killing=500µg/ml | MTS assay | 24 h | Patent |
Hemolytic Activity RBCs: 2.2%Hemolysis=250 µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C48H78N12O9
Absent amino acids CDEGHILMNPQRSTVWY
Common amino acids K
Mass 109226
Pl 11.28
Basic residues 4
Acidic residues 0
Hydrophobic residues 4
Net charge 4
Boman Index -1262
Hydrophobicity -80
Aliphatic Index 25
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7091185B2
Patent Title Periodic antimicrobial peptides
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006
Other Published ID US2005187151A1
External Code
DBAASP ID DBAASPS_13352
This work is licensed under a Creative Commons Attribution 4.0 International License.