This work is licensed under a Creative Commons Attribution 4.0 International License.
KFAK(5)
General Information
DRACP ID DRACP01864
Peptide Name KFAK(5)
Sequence KFAKKFAKKFAKKFAKKFAK
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 89% Killing=500µg/ml | MTS assay | 24 h | Patent |
Hemolytic Activity RBCs: 4.1%Hemolysis=250 µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C120H192N30O21
Absent amino acids CDEGHILMNPQRSTVWY
Common amino acids K
Mass 273011
Pl 11.75
Basic residues 10
Acidic residues 0
Hydrophobic residues 10
Net charge 10
Boman Index -3155
Hydrophobicity -80
Aliphatic Index 25
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7091185B2
Patent Title Periodic antimicrobial peptides
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006
Other Published ID US2005187151A1
External Code
DBAASP ID DBAASPS_13355
This work is licensed under a Creative Commons Attribution 4.0 International License.