LKKL(6)

General Information


DRACP ID  DRACP01875

Peptide Name   LKKL(6)

Sequence  LKKLLKKLLKKLLKKLLKKLLKKL

Sequence Length  24

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HeLa Human papillomavirus-related endocervical adenocarcinoma Carcinoma -1.3% Killing=500µg/ml MTS assay 24 h Patent

Hemolytic Activity  RBCs: 100%Hemolysis=250 µg/ml

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01875

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C144H278N36O25

Absent amino acids  ACDEFGHIMNPQRSTVWY

Common amino acids  KL

Mass  332448

Pl  11.84

Basic residues  12

Acidic residues  0

Hydrophobic residues  12

Net charge  12

Boman Index  -756

Hydrophobicity  -5

Aliphatic Index  195

Half Life 
  Mammalian: 5.5 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US7091185B2

Patent Title  Periodic antimicrobial peptides

Other Iinformation  Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006

Other Published ID  US2005187151A1 




DBAASP ID  DBAASPS_13368

DRACP is developed by Dr.Zheng's team.