This work is licensed under a Creative Commons Attribution 4.0 International License.
LKKL(6)
General Information
DRACP ID DRACP01875
Peptide Name LKKL(6)
Sequence LKKLLKKLLKKLLKKLLKKLLKKL
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | -1.3% Killing=500µg/ml | MTS assay | 24 h | Patent |
Hemolytic Activity RBCs: 100%Hemolysis=250 µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C144H278N36O25
Absent amino acids ACDEFGHIMNPQRSTVWY
Common amino acids KL
Mass 332448
Pl 11.84
Basic residues 12
Acidic residues 0
Hydrophobic residues 12
Net charge 12
Boman Index -756
Hydrophobicity -5
Aliphatic Index 195
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7091185B2
Patent Title Periodic antimicrobial peptides
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006
Other Published ID US2005187151A1
External Code
DBAASP ID DBAASPS_13368
This work is licensed under a Creative Commons Attribution 4.0 International License.