FKA(10)

General Information


DRACP ID  DRACP01892

Peptide Name   FKA(10)

Sequence  FKAFKAFKAFKAFKAFKAFKAFKAFKAFKA

Sequence Length  30

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HeLa Human papillomavirus-related endocervical adenocarcinoma Carcinoma 15% Killing=500µg/ml MTS assay 24 h Patent

Hemolytic Activity  RBCs: 51%Hemolysis=250 µg/ml

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01892

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C180H262N40O31

Absent amino acids  CDEGHILMNPQRSTVWY

Common amino acids  AFK

Mass  399976

Pl  11.75

Basic residues  10

Acidic residues  0

Hydrophobic residues  20

Net charge  10

Boman Index  -760

Hydrophobicity  23.33

Aliphatic Index  33.33

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US7091185B2

Patent Title  Periodic antimicrobial peptides

Other Iinformation  Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006

Other Published ID  US2005187151A1 




DBAASP ID  DBAASPS_13389

DRACP is developed by Dr.Zheng's team.