Syn-BNP (1N)

General Information


DRACP ID  DRACP01904

Peptide Name   Syn-BNP (1N)

Sequence  fxiswSSxWSViX

Sequence Length  13

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HT-29 Colon adenocarcinoma Carcinoma LC>128 µg/ml MTT assay 20 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C10

C-terminal Modification  Free

Other Modification  f=D-Phe; x=D-Orn; i=D-Ile; s=D-Ser; w=D-Trp; X=Orn

Chiral  Mix



Physicochemical Information


Formula  C25H20N6O

Absent amino acids  ACDEFGHIKLMNPQRTY

Common amino acids  S

Mass  74467

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  2

Net charge  0

Boman Index  -383

Hydrophobicity  6.92

Aliphatic Index  22.31

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  458.33

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28055186

Title  Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Doi 10.1021/jacs.6b11861

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_11193

DRACP is developed by Dr.Zheng's team.