This work is licensed under a Creative Commons Attribution 4.0 International License.
Syn-BNP (1N)
General Information
DRACP ID DRACP01904
Peptide Name Syn-BNP (1N)
Sequence fxiswSSxWSViX
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HT-29 | Colon adenocarcinoma | Carcinoma | LC>128 µg/ml | MTT assay | 20 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification C10
C-terminal Modification Free
Other Modification f=D-Phe; x=D-Orn; i=D-Ile; s=D-Ser; w=D-Trp; X=Orn
Chiral Mix
Physicochemical Information
Formula C25H20N6O
Absent amino acids ACDEFGHIKLMNPQRTY
Common amino acids S
Mass 74467
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index -383
Hydrophobicity 6.92
Aliphatic Index 22.31
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 458.33
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28055186
Title Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_11193
This work is licensed under a Creative Commons Attribution 4.0 International License.