Syn-BNP (2S)

General Information


DRACP ID  DRACP01907

Peptide Name   Syn-BNP (2S)

Sequence  kSGxKHKKK

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HT-29 Colon adenocarcinoma Carcinoma LC>128 µg/ml MTT assay 20 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C14OH

C-terminal Modification  Free

Other Modification  k=D-Lys; x=D-Orn

Chiral  Mix



Physicochemical Information


Formula  C35H61N13O7

Absent amino acids  ACDEFILMNPQRTVWY

Common amino acids  K

Mass  91882

Pl  11.28

Basic residues  5

Acidic residues  0

Hydrophobic residues  0

Net charge  5

Boman Index  -2932

Hydrophobicity  -222.22

Aliphatic Index  0

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28055186

Title  Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Doi 10.1021/jacs.6b11861

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_11196

DRACP is developed by Dr.Zheng's team.