Syn-BNP (2. Ala5)

General Information


DRACP ID  DRACP01909

Peptide Name   Syn-BNP (2. Ala5)

Sequence  kLGvALKRK

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HT-29 Colon adenocarcinoma Carcinoma LC>128 µg/ml MTT assay 20 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C14OH

C-terminal Modification  Free

Other Modification  k=D-Lys; v=D-Val

Chiral  Mix



Physicochemical Information


Formula  C35H64N12O6

Absent amino acids  CDEFHIMNPQSTVWY

Common amino acids  KL

Mass  89185

Pl  11.82

Basic residues  3

Acidic residues  0

Hydrophobic residues  3

Net charge  3

Boman Index  -1343

Hydrophobicity  -36.67

Aliphatic Index  97.78

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28055186

Title  Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Doi 10.1021/jacs.6b11861

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_11198

DRACP is developed by Dr.Zheng's team.