Syn-BNP (2. Ala7)

General Information


DRACP ID  DRACP01910

Peptide Name   Syn-BNP (2. Ala7)

Sequence  kLGvPLARK

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HT-29 Colon adenocarcinoma Carcinoma LC>128 µg/ml MTT assay 20 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C14OH

C-terminal Modification  Free

Other Modification  k=D-Lys; v=D-Val

Chiral  Mix



Physicochemical Information


Formula  C34H59N11O6

Absent amino acids  CDEFHIMNQSTVWY

Common amino acids  L

Mass  86079

Pl  11.65

Basic residues  2

Acidic residues  0

Hydrophobic residues  3

Net charge  2

Boman Index  -788

Hydrophobicity  -11.11

Aliphatic Index  97.78

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28055186

Title  Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Doi 10.1021/jacs.6b11861

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_11199

DRACP is developed by Dr.Zheng's team.