This work is licensed under a Creative Commons Attribution 4.0 International License.
Syn-BNP (3.29)
General Information
DRACP ID DRACP01914
Peptide Name Syn-BNP (3.29)
Sequence WyTxXxTwxWXY
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HT-29 | Colon adenocarcinoma | Carcinoma | LC=64 µg/ml | MTT assay | 20 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification C14OH
C-terminal Modification Free
Other Modification y=D-TYR; x(4/6)=D-Orn; w=D-Trp; x(9)=D-Dab; X=Orn
Chiral Mix
Physicochemical Information
Formula C39H31N7O2
Absent amino acids ACDEFGHIKLMNPQRSV
Common amino acids TWX
Mass 104609
Pl 6.09
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index -62
Hydrophobicity -37.5
Aliphatic Index 0
Half Life
/
Extinction Coefficient cystines 12490
Absorbance 280nm 1135.45
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28055186
Title Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_11203
This work is licensed under a Creative Commons Attribution 4.0 International License.