Syn-BNP (3.46)

General Information


DRACP ID  DRACP01915

Peptide Name   Syn-BNP (3.46)

Sequence  XrIRL

Sequence Length  5

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HT-29 Colon adenocarcinoma Carcinoma LC=64 µg/ml MTT assay 20 h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  C14OH

C-terminal Modification  Free

Other Modification  X=Orn; r=D-Arg

Chiral  Mix



Physicochemical Information


Formula  C18H32N6O2

Absent amino acids  ACDEFGHKMNPQSTVWY

Common amino acids  ILRX

Mass  54602

Pl  10.55

Basic residues  1

Acidic residues  0

Hydrophobic residues  2

Net charge  1

Boman Index  -508

Hydrophobicity  76

Aliphatic Index  156

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28055186

Title  Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Doi 10.1021/jacs.6b11861

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  DBAASPS_11204

DRACP is developed by Dr.Zheng's team.